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Make just one mouse left-handed on Mac

Changing the primary mouse button in macOS applies to every connected mouse. If you use one mouse left-handed and another right-handed, or share a Mac, you keep switching it back. EasyMouse stores button settings per device, so you can swap primary and secondary on just one mouse.

Set it up in EasyMouse.

  1. Install EasyMouse and grant Accessibility and Input Monitoring permissions.

  2. Leave the macOS primary button setting at the right-handed default (left).

  3. Select the mouse you use left-handed and turn on "Swap primary and secondary" in its button settings.

  4. Test clicks and right-clicks with that mouse, save, and confirm the other mouse is unchanged.

Before you start.

If you swap buttons in both macOS and EasyMouse, they cancel out. Please change it in only one place.

  • Requires macOS 14 Sonoma or later.
  • Runs on both Apple silicon and Intel-based Macs.
  • One universal build supports both Apple silicon and Intel Macs.
  • Please allow EasyMouse under Accessibility and Input Monitoring in System Settings → Privacy & Security. Please check these permissions again if macOS asks after an update.

Frequently asked questions

Does it affect the trackpad?

No. It applies only to the mouse you selected.

Can side buttons be rearranged for the left hand too?

Yes. In button settings you can assign Back, Forward or other actions to each side button.

Does it switch automatically when I change mice?

Yes. The settings of the mouse you moved last apply automatically, so the button layout follows the mouse.

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Try it with your own mouse.

EasyMouse is free. You can download it and follow this guide on your own mouse. You can download up to three times a day.

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